We are often asked about whether we provide or recommend esketamine as a treatment for depression. Esketamine is a particular form of ketamine, which has been used to treat depression for many years, although the evidence for long-term benefit is lacking. This is not a complete summary of the evidence for ketamine/ esketamine, but it …
We discuss the issue of higher-than-needed doses of antipsychotic medication for augmentation in OCD. This can cause side effects. We briefly review the evidence to support the use of Risperidone in treating OCD and look at typical doses. We go on to make some recommendations for optimum doses of Risperidone. Background In the last year, …
In this blog we look at a recent study of caffeine for treating OCD (Naftalovich, 2020). We provide a bit of background on why caffeine might be used and then we describe the study design, the main findings, before discussing the clinical implications. Introduction How does caffeine affect the body? Essentially, caffeine is a central …
Introduction N-acetylcysteine is thought to regulate glutamate neurotransmission in the brain, and also acts as a potential anti-oxidant. It increases the amount of extracellular glutamate by enhancing the activity of the cystine/ glutamate transporter. There are a number of other drugs that are sometimes used to treat OCD that act on glutamate. These include: Memantine; Riluzole, …