Ninewells Hospital & Medical School, Dundee, DD1 9SY

Blog posts (most recent first)

Novel treatments for OCD: caffeine

In this blog we look at a recent study of caffeine for treating OCD (Naftalovich, 2020). We provide a bit of background on why caffeine might be used and then we describe the study design, the main findings, before discussing the clinical implications. Introduction How does caffeine affect the body? Essentially, caffeine is a central...Continue reading

Novel treatments for depression: psilocybin

There has been a lot of interest in psilocybin as a treatment for several mental disorders, but the evidence is only emerging. In this blog we cover a recent study looking at psilocybin as a treatment for depression (Davis et al, 2020) and discuss what the implications for patient treatment might be. What is psilocybin? Psilocybin...Continue reading

Delays in presenting with OCD

It is widely reported that people with OCD wait a long time before seeking help for their OCD, and they wait even longer before getting effective treatment. The generally-accepted figures are that: People with OCD wait, on average, eleven years with symptoms before they seek help, and; Wait 17 years from onset of OCD to...Continue reading

Evidence review: N-acetylcysteine for OCD

This review has been updated You're reading the older version of this review. Please visit the updated version. Introduction N-acetylcysteine is thought to regulate glutamate neurotransmission in the brain, and also acts as a potential anti-oxidant. It increases the amount of extracellular glutamate by enhancing the activity of the cystine/ glutamate transporter. There are a number...Continue reading

OCD severity in people seen by the AIS

Introduction People sometimes wonder how severe patients being seen by a specialist service are. The following is a description of the severity of symptoms that individuals seen by the AIS present with, based on a relatively large sample of patients seen over the last 14 years. Demographics The data come from 81 patients seen between...Continue reading